Vaginal Cancer: Causes, Symptoms, Types & Treatment

December 20, 2025

Vaginal cancer is a rare but serious type of cancer originating from the tissues of the vagina. Unlike other cancers of the reproductive system, it is necessary to be aware that early detection makes a great difference in treatment. Due to the nature of their symptoms, many women simply do not report them, thinking of minor infections or hormonal changes. Therefore, vaginal cancer symptoms often go unnoticed until they progress and become life-threatening. Learning about the signs and causes, along with treatment options, is therefore critical.

Causes & Risk Factors of Vaginal Cancer

Various risk factors predispose many women to vaginal cancer. Awareness of risk factors is often the beginning of early diagnosis.

1. HPV Infection

The most significant cause of vaginal cancer is the Human Papillomavirus. Persistent high-risk type strains of the virus can cause cell abnormalities, which, over time, can develop into cancer.

2. Smoking

Tobacco causes weakness in vaginal tissues and reduces the body's resistance to cellular damage caused by HPV. It interferes with immune functions and increases cancer risks.

3. Age & Previous Cancer Treatments

Vaginal cancer most often affects women older than age 60. Having had cervical cancer, radiation therapy to the pelvic area, or a precancerous lesion detected increases a woman's risk for vaginal cancer later in her life.

4. Immunosuppression & Chronic Irritation

Risk factors include women who are immunocompromised, such as those with HIV, autoimmune disorders, or long-term steroid use. It might also be due to chronic irritation of the vaginal lining.

Symptoms of Vaginal Cancer

Spotting early vaginal cancer symptoms makes the treatment more effective. Common symptoms of this disease include:

Abnormal Vaginal Bleeding or Discharge

This may be after intercourse, between periods, or after menopause. Other signs include persistent watery or foul-smelling discharge.

Pelvic Pain, Pressure, or Discomfort

Lower abdominal pain, painful sexual intercourse, or persistent pelvic pressure may be symptoms of abnormal tissue growth.

Painful Urination or Bowel Movements

It can cause discomfort and burning, especially when passing urine or stool from the rectum.

Vaginal tumour is present

Some symptoms can be a lump or mass inside the vagina. A tumour in vagina may feel like a firm and irregular growth; in advanced stages, a tumour may be visible by self-examination or gynaecological checkups.

Knowledge of vaginal cancer symptoms enables women to know when to seek medical attention.

Types of Vaginal Cancer

Squamous Cell Carcinoma

This is the most common type. It develops in the thin, flat cells lining the vagina and usually grows slowly.

Adenocarcinom

This type begins in the glandular cells of the vagina. It is less common, yet the risk of its dissemination is higher.

Rare Types

  • Melanoma comes from pigment-producing cells.
  • Sarcoma, arising from connective tissue
  • Small cell carcinoma and other variants are unusual

The type of therapy applied to vaginal cancer will depend on the subtype as well as the stage.

Also Read: Early Warning Signs of Cervical Cancer

Diagnosis & Screening

Although there is no routine screening test for vaginal cancer, several diagnostic tools can identify the condition early:

Pelvic exam & Pap test

Abnormalities of the vagina and cervix are looked for during a pelvic exam. In some cases, a Pap test can show abnormal cells, which may mean vaginal precancerous changes.

Biopsy

A small tissue sample is taken if a suspicious lesion is seen to confirm whether it is cancerous.

Imaging

Tests such as MRI, CT scans, and PET scans are performed to ascertain the cancer’s stage and whether it has spread.

Also Read: Pap smear -Mandatory cervical cancer screening

Treatment Options

Treatment depends on the stages, types, and general condition of the patient, depending on the cause.

1. Surgery

Small, early-stage tumours may be surgically removed. When the cancer is more advanced, treatment may involve the partial or complete removal of the vagina.

2. Radiation Therapy

The most common treatment for vaginal cancer is radiation, sometimes given alone, but more often after surgery. Internal radiation (brachytherapy) is sometimes used for deeper tissues.

3. Chemotherapy

For advanced or recurrent cancer, chemotherapy may be used alone or combined with radiation.

4. Targeted Therapy & Immunotherapy

These options are increasingly used in late-stage or treatment-resistant cases.

Book an online appointment with Dr. Sahana Hegde for Pregnancy & Gynecology related issues.

Prognosis & Prevention

Early diagnosis of vaginal cancer offers a far better prognosis.

Prevention Tips

  • HPV vaccination greatly reduces risk
  • Avoiding smoking lowers cancer risk.
  • Managing health conditions that weaken the immune system

What Sets Cloudnine Apart

Cloudnine provides state-of-the-art gynaecologic care supported by expert oncologists, modern diagnostic facilities, and personalised treatment planning. From early diagnosis to surgical and non-surgical treatment, Cloudnine ensures precision, comfort, and continuous care. Their multidisciplinary team collaborates to provide safe, compassionate, and evidence-based care to women suffering from symptoms or diagnosed conditions related to vaginal cancer.

Conclusion

Vaginal cancer is a condition that demands awareness and timely clinical review. Understanding its causes, early symptoms, and modes of treatment greatly improves outcomes. Knowledge regarding vaginal cancer and what does vaginal cancer look like aids women in safeguarding their reproductive health. In case of unusual bleeding, pelvic pain, discharge, or a lump felt in the vagina, promptly contact a gynaecologic oncologist as soon as possible.

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Frequently Asked Questions

1. What is the first stage of vaginal cancer?

Stage I cancer of the vagina is confined to the vaginal wall and does not extend beyond.

2. What does vaginal cancer look like?

It may appear as a lump, ulcer, raised lesion, or discoloured patch inside the vagina.

3. What are the symptoms of vaginal cancer?

Irregular bleeding, pelvic pain, unusual discharge, painful urination, and vaginal lumps.

4. What behaviour does a cancer woman exhibit?

There is no particular behavioural pattern. Emotional and physical changes vary according to the symptoms, diagnosis, and condition of the patient.

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