Unexplained Infertility | Less ovarian reserve

"What is unexplained infertility? When a couple cannot conceive after one year of regular intercourse and all the routine investigations are normal. Like they have normal semen analysis. Fallopian body tubes are patent and ovulation is also happening. If everything is normal despite this if a couple cannot conceive. We call it unexplained infertility. Almost 25 to 30% of cases of infertility have an unexplained factor. This could be because of some hidden factors. There could be mild tube dysfunction. Tubes could be patent. But there could be some mild tube dysfunction. There could be mild endometrosis, could be because of less ovarian reserve or advanced age even there could be some autoimmune or genetic factors in male partner. It could be because of defects in the sperm function test. If the count is normal, motility and morphology are also normal. But somehow sperm is unable to fertilize the egg. So such patients can have unexplained infertility. treatment of such couple depends on the duration of infertility and the woman's age. If the age is less than 35 years and the duration of infertility is less than 2 years, such couples can conceive mild for treatment in the form of ovulation induction plus III. So we do ovulation induction and III for 3 to four cycles and most couples will conceive with this treatment. If they cannot conceive with III. Then we proceed with IVF but if the age is more than 38 years in such couples with unexplained infertility, immediate IVF is advisable"