Are there treatments available for Genetic Disorders?

"With the advances in clinical genetics there are many exciting vistas that are opening up. Disorders which were not treatable are now coming into the areana of treatable genetic disorders. The list of inborn errors of metabolism which can have treatment, the number has gone up from 40 to 80’s to a 100 now. There are conditions called as thalassemia which are amenable to bone marrow transplant. A lot of metabolic conditions like Crabbe disease or storage disorder like Gaucher, mucopolysaccharidosis, are now amenable to special therapy in the form of enzyme replacement therapy. This is a treatment in which the defective enzyme, which is causing all these symptoms are administered exogenously, and the symptoms abate. While there is good news that there is a lot of new treatment models being available in the last few years, but overall there is many condition for which we do not have any cure, for example, Downs Syndrome which is caused by 3 copies of Chromosome 21, there is no treatment for Downs Syndrome, but yes, we can support the various spectrums which is associated with Downs syndrome. If the child has got refractive errors, you correct that, if the child has hearing issues, you give him aids, all these can go a long way in improving the child’s quality of life overall and reducing the morbidity of the disease. While treatment options are available for some, for some it is only about the routine surveillance and improving the quality of life"